Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 14/20 | 0.46 |
| ▸ | RBBP4 | Q09028 | 14/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 14/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 14/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 14/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21251364 | 0.89 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964944 | 0.89 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964531 | 0.86 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886541 | 0.85 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886549 | 0.85 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964960 | 0.83 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964849 | 0.82 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964860 | 0.82 | EED (0.51) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964901 | 0.82 | EED (0.65) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964783 | 0.81 | EED (0.42) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |