Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 16/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 16/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 16/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 16/20 | 0.42 |
| ▸ | AEBP2 | Q6ZN18 | 16/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986128 | 0.90 | EED (0.41) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964782 | 0.87 | EED (0.42) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21156102 | 0.82 | EED (0.53) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964671 | 0.81 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964766 | 0.81 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21251308 | 0.81 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964391 | 0.81 | EED (0.61) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964944 | 0.80 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21251364 | 0.80 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964531 | 0.79 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| EP-3524602-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |