Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964533 | 0.71 | ALDH1A1 (0.48) | — | |
| SCHEMBL19964946 | 0.66 | CYP1A2 (0.35) | — | |
| SCHEMBL21251324 | 0.66 | — | — | |
| SCHEMBL17773153 | 0.62 | MAPT (0.46) | — | |
| SCHEMBL2609401 | 0.61 | CYP2A6 (0.42) | JAK2 | |
| SCHEMBL2737364 | 0.61 | PLAU (0.43) | JAK2 | |
| SCHEMBL20032189 | 0.60 | MAPT (0.34) | JAK2 | |
| SCHEMBL22822736 | 0.60 | MAP3K5 (0.41) | — | |
| SCHEMBL14063586 | 0.60 | DYRK1A (0.51) | — | |
| SCHEMBL21342369 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |