Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965170 | 0.69 | KDM4E (0.39) | KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL21124462 | 0.68 | FFAR4 (0.45) | HTTLMNAPOLBMAPTALDH1A1 | |
| SCHEMBL30918019 | 0.66 | CASP6 (0.42) | HTTLMNAKMT2AMAPTL3MBTL1 | |
| SCHEMBL8572367 | 0.65 | DRD1 (0.40) | HTTLMNAKMT2AGRIN2DGRIN3B | |
| SCHEMBL19155132 | 0.65 | NPC1 (0.38) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL29406937 | 0.65 | NPC1 (0.38) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL12344127 | 0.62 | HTT (0.51) | HTTPOLBKMT2AMAPTKDM4E | |
| SCHEMBL3410110 | 0.62 | HTT (0.51) | HTTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29826722 | 0.62 | HTT (0.51) | HTTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL3409761 | 0.61 | HTT (0.50) | HTTKMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049324-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |