Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19958801 | 1.00 | TSHR (0.41) | TSHREPHX2SMN1; SMN2FDPSCHRNB4 | |
| SCHEMBL2492654 | 0.95 | FDPS (0.44) | TSHREPHX2SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL645074 | 0.93 | FDPS (0.42) | TSHREPHX2SMN1; SMN2FDPS | |
| SCHEMBL29410746 | 0.88 | TSHR (0.44) | TSHREPHX2SMN1; SMN2 | |
| SCHEMBL3441726 | 0.85 | TSHR (0.44) | TSHREPHX2SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL699791 | 0.83 | TSHR (0.42) | TSHREPHX2SMN1; SMN2FDPS | |
| SCHEMBL24740457 | 0.83 | TDP1 (0.42) | TSHRFDPS | |
| SCHEMBL19958799 | 0.83 | TDP1 (0.42) | TSHRFDPS | |
| SCHEMBL2044063 | 0.83 | TDP1 (0.42) | TSHRFDPS | |
| SCHEMBL1584792 | 0.81 | FDPS (0.40) | TSHREPHX2FDPSCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049271-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2018-03-15 | — | — | WO | disclosed |