Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345168 | 0.85 | PDE10A (0.82) | PDE10A | |
| SCHEMBL10345175 | 0.81 | PDE10A (0.73) | PDE10A | |
| SCHEMBL10345047 | 0.78 | PDE10A (0.70) | PDE10A | |
| SCHEMBL10309394 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL10309378 | 0.75 | PDE10A (0.66) | PDE10A | |
| SCHEMBL10309454 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL10309435 | 0.73 | PDE10A (0.72) | PDE10A | |
| SCHEMBL10309402 | 0.73 | PDE10A (0.61) | PDE10A | |
| SCHEMBL10345615 | 0.73 | PDE10A (0.78) | PDE10A | |
| SCHEMBL10309383 | 0.73 | PDE10A (0.63) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072759-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072759-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GPR119, NLN | PDE10A 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.