Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965179 | 0.90 | ACE (0.47) | ACEALDH1A1MME | |
| SCHEMBL19965093 | 0.81 | ACE (0.46) | ACEALDH1A1SCN9A | |
| SCHEMBL19966643 | 0.81 | SCN9A (0.42) | ACESCN9A | |
| SCHEMBL19965078 | 0.77 | SCN9A (0.42) | ACEMMESCN9A | |
| SCHEMBL19965180 | 0.77 | ACE (0.39) | ACE | |
| SCHEMBL22472825 | 0.76 | ACE (0.42) | ACEMMESCN9A | |
| SCHEMBL19965087 | 0.75 | SCN9A (0.44) | ACEMMESCN9A | |
| SCHEMBL6178534 | 0.74 | CCKBR (0.48) | — | |
| SCHEMBL22472826 | 0.74 | CCKAR (0.38) | ACEMMESCN9A | |
| SCHEMBL19966664 | 0.73 | CCKAR (0.36) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049129-A1 | CHOLECYSTOKININ 2 RECEPTOR TARGETED NIR IMAGING AND USE THEREOF | On Target Laboratories, LLC (US) | 2018-03-15 | — | — | WO | disclosed |