Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961192 | 0.79 | HPGD (0.60) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9491918 | 0.77 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4495740 | 0.77 | KDM4E (0.73) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11523761 | 0.77 | KDM4E (0.73) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL20336230 | 0.77 | KDM4E (0.73) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL29449726 | 0.77 | KDM4E (0.73) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11521138 | 0.75 | KDM4E (0.69) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL720266 | 0.73 | HDAC3 (0.50) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL19949398 | 0.73 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19949399 | 0.73 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049129-A1 | CHOLECYSTOKININ 2 RECEPTOR TARGETED NIR IMAGING AND USE THEREOF | On Target Laboratories, LLC (US) | 2018-03-15 | — | — | WO | disclosed |