SCHEMBL4495740

SCHEMBL4495740

c1ccc(NC2CCCCC2)c(NC2CCCCC2)c1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.73
GAA P10253 2/20 0.73
MAPT P10636 1/20 0.73
IDO1 P14902 1/20 0.58
HSD17B10 Q99714 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
HTT P42858 3/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 2/20 0.50
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
NSD2 O96028 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20336230 1.00 KDM4E (0.73) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL29449726 1.00 KDM4E (0.73) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL11523761 1.00 KDM4E (0.73) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL11521138 0.97 KDM4E (0.69) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL1496027 0.89 KDM4E (0.61) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL11347783 0.86 MAPT (0.58) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL3691601 0.86 MAPT (0.58) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL23016005 0.85 KDM4E (1.00) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL17874938 0.85 KDM4E (1.00) KDM4EGAAMAPTIDO1HSD17B10
SCHEMBL7634561 0.85 GAA (0.61) KDM4EGAAMAPTIDO1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3149059-B1 USE OF COPOLYMERS OR POLYMERS CONTAINING OXO IMIDE MOIETIES AS FLAME RETARDANTS, STABILISERS, RHEOLOGY MODIFIERS FOR RESINS, INITIATORS FOR POLYMERISATION AND GRAFTING, CROSS-LINKING AGENTS OR COUPLERS AS WELL AS MOULDING MATTERS CONTAINING SUCH (CO)POLYMERS FRAUNHOFER GES FORSCHUNG (DE) 2018-09-12 EP claimed
US-20240191060-A1 RUBBER MIXTURES CONTAINING N,N'-DIALKYL-P-PHENYLENEDIAMINES LANXESS DEUTSCHLAND GMBH (DE) 2024-06-13 US disclosed
EP-4067112-A1 RUBBER MIXTURES CONTAINING N, Ný -DIALKYL-P-PHENYLENEDIAMINES LANXESS Deutschland GmbH (DE) 2022-10-05 EP disclosed
EP-3484983-B1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING MIXTURE OF ANTIOXIDANTS CHEVRON ORONITE CO (US) 2020-05-27 EP disclosed
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed
US-6767949-B1 REDUCING AGENT COMPRISING PHOSPHORUS COMPOUND, SULFUR COMPOUND OR ETHYLENICALLY UNSATURATED CYCLIC COMPOUND; DISCOLORATION INHIBITION CIBA SPECIALTY CHEMICALS CORPORATION 2004-07-27 US disclosed
US-4140718-A Preparation of N,N'-dialkylphenylenediamines UOP INC. (US) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S KDM4E 4043/4885GAA 3581/4885MAPT 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.