Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19835720 | 0.82 | LMNA (0.44) | KDM4EHTTALDH1A1GAANPC1 | |
| SCHEMBL18105164 | 0.82 | LMNA (0.44) | KDM4EHTTALDH1A1GAANPC1 | |
| SCHEMBL18105158 | 0.80 | MAPK1 (0.46) | HTTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL19835963 | 0.80 | MAPK1 (0.46) | HTTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18104942 | 0.80 | LMNA (0.43) | KDM4EHTTNPC1RAB9APAK4 | |
| SCHEMBL19836122 | 0.80 | LMNA (0.43) | KDM4EHTTNPC1RAB9APAK4 | |
| SCHEMBL29582930 | 0.80 | LMNA (0.43) | KDM4EHTTNPC1RAB9APAK4 | |
| SCHEMBL19949365 | 0.80 | LMNA (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18104971 | 0.80 | LMNA (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18104897 | 0.80 | HDAC4 (0.53) | PAK4CDK2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072708-A1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072708-A1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | APP, BACE1, PSEN1 | KDM4E 2555/4885HTT 18/4885ALDH1A1 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.