Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.50 |
| ▸ | KDM5A | P29375 | 5/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178799 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL9017477 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL17817138 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL4925384 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL16918405 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL15254653 | 0.98 | EPHX2 (0.62) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL14558610 | 0.98 | EPHX2 (0.62) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL23343387 | 0.96 | EPHX2 (0.70) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL8704909 | 0.96 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL11775303 | 0.96 | EPHX2 (0.70) | EPHX2ALDH1A1CNR1KDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049042-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCERS BY INHIBITING ESTROGEN SIGNALING IN MYELOID-DERIVED SUPPRESSOR CELLS | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2018-03-15 | — | — | WO | disclosed |