Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.50 |
| ▸ | KDM5A | P29375 | 5/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178799 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL9017477 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL19968581 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL4925384 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL16918405 | 1.00 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL15254653 | 0.98 | EPHX2 (0.62) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL14558610 | 0.98 | EPHX2 (0.62) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL23343387 | 0.96 | EPHX2 (0.70) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL8704909 | 0.96 | EPHX2 (0.65) | EPHX2ALDH1A1CNR1KDM4CKDM5A | |
| SCHEMBL11775303 | 0.96 | EPHX2 (0.70) | EPHX2ALDH1A1CNR1KDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | EPHX2 882/4885ALDH1A1 999/4885CNR1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.