Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962152 | 0.94 | PDE10A (0.34) | PDE10ATAS1R3TAS1R1 | |
| SCHEMBL19962073 | 0.94 | PDE10A (0.30) | PDE10A | |
| SCHEMBL19962082 | 0.87 | SYK (0.34) | PDE10ATAS1R3TAS1R1 | |
| SCHEMBL19969339 | 0.87 | SYK (0.34) | PDE10ATAS1R3TAS1R1 | |
| SCHEMBL19969193 | 0.86 | PDE10A (0.31) | PDE10A | |
| SCHEMBL19969237 | 0.86 | PDE10A (0.31) | PDE10A | |
| SCHEMBL18180305 | 0.84 | — | — | |
| SCHEMBL19968967 | 0.84 | — | — | |
| SCHEMBL18180271 | 0.81 | SYK (0.31) | PDE10A | |
| SCHEMBL19969198 | 0.81 | SYK (0.31) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072997-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072997-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2H, POLR2E | PDE10A 2805/4885TAS1R3 4630/4885TAS1R1 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.