Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367696 | 1.00 | AKR1C1 (0.61) | AKR1C1AKR1C2AKR1C3KMT2APTGS2 | |
| SCHEMBL2555171 | 1.00 | AKR1C1 (0.61) | AKR1C1AKR1C2AKR1C3KMT2APTGS2 | |
| SCHEMBL28354228 | 0.88 | AKR1C1 (0.50) | AKR1C1AKR1C2AKR1C3KMT2APTGS2 | |
| SCHEMBL8894614 | 0.87 | POLB (0.57) | AKR1C1KMT2APTGS2ALDH1A1MEN1 | |
| SCHEMBL28000528 | 0.85 | AKR1C1 (0.50) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL9298954 | 0.85 | AKR1C1 (0.50) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL8734925 | 0.83 | CES2 (0.59) | AKR1C1ALDH1A1CES2CES1TSHR | |
| SCHEMBL8734921 | 0.83 | CES2 (0.59) | AKR1C1ALDH1A1CES2CES1TSHR | |
| SCHEMBL11437339 | 0.83 | CES2 (0.56) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL11437343 | 0.83 | CES2 (0.56) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812029-B | Preparation method of crotonate compounds | 台州臻挚生物科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| EP-1747059-A1 | PERVAPORATION COMPOSITE MEMBRANES | McMaster University (CA) | 2007-01-31 | — | — | EP | claimed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| WO-2005102503-A1 | PERVAPORATION COMPOSITE MEMBRANES | MCMASTER UNIVERSITY (CA) | 2005-11-03 | — | — | WO | claimed |
| EP-0758322-B1 | ALPHA-(PYRAZOL-3-YL)-OXYMETHYLENE-PHENYLBUTENIC ACID METHYL ESTERS AND THE USE THEREOF AGAINST HARMFUL FUNGI OR ANIMAL PESTS | BASF AG (DE) | 2001-09-05 | — | — | EP | claimed |
| CN-119220204-A | Preparation method of sodium ion positive electrode binder | 无锡安钠能源技术有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-3674306-B1 | THIENOPYRIDINE DERIVATIVES CONTAINING AN ETHYLENIC ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF | TIANJIN INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| CN-112812029-B | Preparation method of crotonate compounds | 台州臻挚生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-112812029-B | Preparation method of crotonate compounds | 台州臻挚生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20230151128-A1 | NEAR INFRARED (NIR) LIGHT CONTROLLED RUTHENIUM CATALYZED OLEFIN METATHESIS | NATIONAL SCIENCE FOUNDATION | 2023-05-18 | — | — | US | disclosed |
| WO-2023287964-A1 | LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-01-19 | — | — | WO | disclosed |
| US-11466025-B2 | Thienopyridine derivatives containing unsaturated aliphatic olefinic bond, preparation method and use thereof | TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2022-10-11 | — | — | US | disclosed |
| WO-2004007417-A1 | ENZYME INHIBITORS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2004-01-22 | — | — | WO | disclosed |
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1334083-A2 | 1,4-DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2002017712-A2 | DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| US-5922710-A | Iminooxybenzylcrotonate esters, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-13 | — | — | US | disclosed |
| US-4652653-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4612378-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | AKR1C1 173/4885AKR1C2 285/4885AKR1C3 169/4885 |
| US-11466025-B2 | Thienopyridine derivatives containing unsaturated aliphatic olefinic bond, preparation method and use thereof | PTGIR, TBXA2R, PTGER1 | AKR1C1 548/4885AKR1C2 648/4885AKR1C3 326/4885 |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | AKR1C1 173/4885AKR1C2 285/4885AKR1C3 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.