Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401562 | 0.91 | MAPT (0.52) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL29170202 | 0.89 | PPARG (0.48) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL7903853 | 0.89 | PPARG (0.48) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL28252735 | 0.88 | MAPT (0.49) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL13574956 | 0.88 | MGLL (0.51) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL28252736 | 0.88 | MAPT (0.49) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL28776874 | 0.86 | MAPT (0.48) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL19967916 | 0.86 | MAPT (0.48) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL20631080 | 0.86 | MAPT (0.59) | PPARGPPARAMGLLMAPTALDH1A1 | |
| SCHEMBL6624647 | 0.86 | MAPT (0.59) | PPARGPPARAMGLLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047139-A1 | COMPOUNDS AS MODULATORS OF TIGIT SIGNALLING PATHWAY | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-15 | — | — | WO | disclosed |