Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26439807 | 1.00 | RXFP1 (0.51) | RXFP1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL10825997 | 0.94 | RXFP1 (0.54) | RXFP1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL19969451 | 0.92 | RXFP1 (0.57) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL19969448 | 0.91 | RXFP1 (0.59) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL25155042 | 0.85 | RXFP1 (0.51) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL26439802 | 0.85 | RXFP1 (0.51) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL19969447 | 0.84 | RXFP1 (0.62) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL15071609 | 0.83 | CYP1A2 (0.56) | RXFP1MAOBMAOAKMT2AMEN1 | |
| SCHEMBL19969387 | 0.83 | RXFP1 (0.52) | RXFP1MAOBMAOAKMT2ACYP2C19 | |
| SCHEMBL28064034 | 0.80 | CYP1A2 (0.57) | RXFP1MAOBMAOAKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045464-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2018-03-15 | — | — | WO | disclosed |