Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738967 | 0.77 | BRD4 (0.41) | — | |
| SCHEMBL4014501 | 0.64 | BRD4 (0.38) | NPBWR1MCHR1 | |
| SCHEMBL16739019 | 0.62 | BRD4 (0.43) | — | |
| SCHEMBL4013172 | 0.62 | MAPK14 (0.46) | — | |
| SCHEMBL3864307 | 0.60 | DGAT1 (0.42) | NPBWR1MCHR1 | |
| SCHEMBL16738900 | 0.60 | BRD4 (0.44) | — | |
| SCHEMBL15771930 | 0.59 | BRD4 (0.46) | — | |
| SCHEMBL16738996 | 0.59 | BRD4 (0.41) | — | |
| SCHEMBL16739044 | 0.58 | BRD4 (0.40) | — | |
| SCHEMBL16739049 | 0.58 | BRD4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9918990-B2 | Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors | INCYTE CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |