SCHEMBL1997075

SCHEMBL1997075

CCOC(=O)c1cc(F)ccc1F

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.60
HPGD P15428 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
MAPK1 P28482 1/20 0.60
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 3/20 0.50
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
JMJD6 Q6NYC1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4628672 0.87 TSHR (0.60) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL367075 0.86 TSHR (0.57) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL30755337 0.86 TSHR (0.57) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL5739621 0.86 TSHR (0.53) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL10562029 0.86 TSHR (0.57) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL11768705 0.84 CA12 (0.57) TSHRMEN1KMT2AKDM4ECA12
SCHEMBL19971601 0.84 MAPK1 (0.52) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL3895996 0.84 CA12 (0.70) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL11933660 0.84 TSHR (0.56) TSHRHPGDMEN1KMT2ANPSR1
SCHEMBL12093159 0.84 CA12 (0.70) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946303-A Catalyst, preparation method thereof, method for regulating and controlling ethylene polymerization kinetics behavior and application 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-114865080-A Lithium ion battery electrolyte and lithium ion battery 香河昆仑新能源材料股份有限公司 2022-08-05 CN claimed
CN-117946303-A Catalyst, preparation method thereof, method for regulating and controlling ethylene polymerization kinetics behavior and application 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-117946304-A Spherical catalyst component containing fluoroester electron donor, preparation method, catalyst and application thereof in ethylene polymerization 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-114865080-A Lithium ion battery electrolyte and lithium ion battery 香河昆仑新能源材料股份有限公司 2022-08-05 CN disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-3966728-A ANTIPEPTIC ULCER ACTIVITY NIPPON SHINYAKU CO., LTD. (JA) 1976-06-29 US disclosed