Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 5/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP6 | Q2NL67 | 3/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970888 | 0.95 | GNRHR (0.41) | SLC2A1MAOBGNRHRTACR2HRH2 | |
| SCHEMBL19982583 | 0.92 | SLC2A1 (0.42) | SLC2A1HDAC6CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19970854 | 0.89 | MAOB (0.48) | SLC2A1MAOBGNRHRTACR2HRH2 | |
| SCHEMBL19970747 | 0.89 | DRD4 (0.45) | SLC2A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19982610 | 0.88 | SLC2A1 (0.42) | SLC2A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19982656 | 0.87 | DRD4 (0.42) | SLC2A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19982561 | 0.86 | SLC2A1 (0.46) | SLC2A1MAOBGNRHRTACR2HRH2 | |
| SCHEMBL19970820 | 0.85 | DRD4 (0.43) | SLC2A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19970850 | 0.84 | GNRHR (0.47) | SLC2A1MAOBGNRHRTACR2HRH2 | |
| SCHEMBL19970804 | 0.83 | CNR2 (0.40) | SLC2A1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |