(-)-Epicatechin

(-)-Epicatechin

SCHEMBL19971115

O=C(O)c1cc(O)c(O)c(O)c1.Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@H](O)C2

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 8/20 0.76
KDM4E B2RXH2 6/20 0.76
SNCA P37840 5/20 0.76
HSD17B10 Q99714 4/20 0.76
MAPT P10636 4/20 0.76
RECQL P46063 4/20 0.76
PKM P14618 4/20 0.76
GAA P10253 3/20 0.76
ALDH1A1 P00352 3/20 0.76
APEX1 P27695 3/20 0.76
MEN1 O00255 3/20 0.76
KMT2A Q03164 3/20 0.76
RAD52 P43351 3/20 0.76
ALOX15 P16050 3/20 0.76
TDP1 Q9NUW8 3/20 0.76
ALPL P05186 2/20 0.76
POLB P06746 2/20 0.76
PTGS1 P23219 2/20 0.76
HPGD P15428 2/20 0.76
APP P05067 2/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechin SCHEMBL7198386 1.00 BACE1 (0.76) BACE1KDM4ESNCAHSD17B10MAPT
Catechin SCHEMBL9311459 1.00 BACE1 (0.76) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL27997178 1.00 BACE1 (0.76) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL144001 1.00 BACE1 (0.76) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL7538738 1.00 BACE1 (0.76) BACE1KDM4ESNCAHSD17B10MAPT
(-)-Epicatechin SCHEMBL28608623 0.99 KDM4E (0.77) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL3359334 0.91 BACE1 (0.80) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL28937698 0.89 SYNJ2 (0.78) BACE1KDM4ESNCAHSD17B10MAPT
Cianidanol SCHEMBL21611697 0.89 SYNJ2 (0.78) BACE1KDM4ESNCAHSD17B10MAPT
(-)-Epicatechin SCHEMBL29137174 0.89 SYNJ2 (0.78) BACE1KDM4ESNCAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114452840-B Graphene oxide modified separation membrane based on electrostatic spraying and preparation and application thereof 中山大学 2023-06-16 CN claimed
CN-111085119-B Modified separation membrane for membrane distillation and preparation method and application thereof 中山大学 2021-09-21 CN claimed
CN-111097474-A Preparation method of polyphenol or aromatic carboxylic acid for universal construction of single-atom and atom-dispersed multi-metal catalyst 江苏大学 2020-05-05 CN claimed
CN-111085119-A Modified separation membrane for membrane distillation and preparation method and application thereof 中山大学 2020-05-01 CN claimed
CN-110438255-A A kind of molecular labeling site that Tea tree epicatechin gallic acid ester content is chain and its application TEA RES INST GUANGDONG ACADEMY AGRICULTURAL SCIENCES 2019-11-12 CN claimed
CN-108816689-A A kind of super-hydrophilic coating and preparation method thereof with long acting antibiotic performance 四川大学 2018-11-16 CN claimed
CN-107823721-A Balloon surface coating 卡迪奥诺沃姆有限公司 2018-03-23 CN claimed
CN-107823719-A Balloon surface coating 卡迪奥诺沃姆有限公司 2018-03-23 CN claimed
CN-107823720-A Balloon surface coating 卡迪奥诺沃姆有限公司 2018-03-23 CN claimed
CN-106560702-A Wuyi rock tea production place identification method through combination of electronic tongue and chromatographic separation technology 中国计量大学 2017-04-12 CN claimed
CN-1717268-A The nutritional supplement composition that contains gallic acid epicatechin and raspberry ketone DSM IP ASSETS BV (NL) 2006-01-04 CN claimed
CN-1115143-C Cosmetic composition KAO CORP (JP) 2003-07-23 CN claimed
CN-1166135-A Cosmetic compsns. KAO CORP (JP) 1997-11-26 CN claimed
WO-2023125519-A1 NEW APPLICATION OF PLANT-DERIVED ALKALINE PHOSPHATASE EXPRESSION PROMOTER 香港科技大学 2023-07-06 WO disclosed
CN-112553288-B Method for screening natural products with anti-aging potential 汤臣倍健股份有限公司 2022-06-07 CN disclosed
CN-112760327-B Persimmon procyanidine precursor transmembrane transporter DkMATE5 and application thereof 华中农业大学 2022-02-11 CN disclosed
CN-1394562-A Absorbing products UNI CHARM CORP (JP) 2003-02-05 CN disclosed
CN-1365857-A Ore dressing chemical prepared from tea leaf UNIV ZHONGNAN (CN) 2002-08-28 CN disclosed
CN-1274026-A Method of producing antibiotic fiber ITOHSONO CO LTD (JP) 2000-11-22 CN disclosed
CN-1179104-A Method of treating or preventing non-viral microbial infection JLB INC (US) 1998-04-15 CN disclosed