Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867206 | 0.87 | BBOX1 (0.47) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL35503 | 0.87 | TSHR (0.47) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16799372 | 0.85 | TSHR (0.50) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16799079 | 0.84 | TSHR (0.53) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL18151644 | 0.84 | TSHR (0.53) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16798999 | 0.84 | TSHR (0.53) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16799087 | 0.84 | TSHR (0.53) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16798995 | 0.84 | TSHR (0.53) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16971017 | 0.82 | TSHR (0.42) | BBOX1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19971271 | 0.82 | BBOX1 (0.42) | BBOX1TSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530286-B2 | Sulfobetaine-based protein aggregation inhibitor for use in preventing aggregation of a protein | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2022-12-20 | — | — | US | disclosed |
| US-10995160-B2 | Protein aggregation inhibitor | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2021-05-04 | — | — | US | disclosed |
| US-20200332044-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2020-10-22 | — | — | US | disclosed |
| US-20190161563-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
| US-20180118859-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2018-05-03 | — | — | US | disclosed |
| EP-3296314-A1 | PROTEIN AGGREGATION INHIBITOR | Osaka Organic Chemical Industry Ltd. (JP) | 2018-03-21 | — | — | EP | disclosed |