SCHEMBL1997165

SCHEMBL1997165

CCN(c1ccnc(-c2cnc3ccc(F)cn23)n1)C1CCCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EIF2AK4 Q9P2K8 18/20 0.48
ADORA2A P29274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997166 1.00 EIF2AK4 (0.48) EIF2AK4ADORA2A
SCHEMBL1996002 0.93 EIF2AK4 (0.47) EIF2AK4
SCHEMBL1993019 0.90 EIF2AK4 (0.50) EIF2AK4
SCHEMBL1993022 0.90 EIF2AK4 (0.50) EIF2AK4
SCHEMBL1993296 0.87 EIF2AK4 (0.46) EIF2AK4
SCHEMBL12643818 0.87 EIF2AK4 (0.43) EIF2AK4ADORA2A
SCHEMBL1996140 0.85 EIF2AK4 (0.42) EIF2AK4ADORA2A
SCHEMBL2032642 0.81 EIF2AK4 (0.46) EIF2AK4ADORA2A
SCHEMBL2000295 0.80 EIF2AK4 (0.47) EIF2AK4
SCHEMBL2000293 0.80 EIF2AK4 (0.47) EIF2AK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130216498-A1 IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS ALMIRALL, S.A. (ES) 2013-08-22 US disclosed
EP-2338888-A1 Imidazopyridine derivatives as JAK inhibitors Almirall, S.A. (ES) 2011-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130216498-A1 IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS JAK1, JAK2, JAK3 EIF2AK4 211/4885ADORA2A 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.