SCHEMBL19971761

SCHEMBL19971761

Cc1ccc(NC(=O)NS(=O)(=O)Nc2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA12 O43570 2/20 0.56
CA4 P22748 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
TP53 P04637 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA13 Q8N1Q1 1/20 0.56
CA14 Q9ULX7 1/20 0.56
PTPN7 P35236 1/20 0.56
LMNA P02545 2/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 2/20 0.54
RAB9A P51151 2/20 0.54
PPARG P37231 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
NR2E3 Q9Y5X4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21641976 0.89 NPC1 (0.51) CA1CA2CA12CA4CA7
SCHEMBL19971753 0.81 ACP1 (0.67) CA1CA2CA12CA9TP53
SCHEMBL23486690 0.81 CA12 (0.59) CA1CA2CA12CA4CA7
SCHEMBL20568276 0.80 CA12 (0.76) CA1CA2CA12CA4CA7
SCHEMBL28184732 0.80 CA1 (0.55) CA1CA2CA12CA4CA7
SCHEMBL608230 0.80 CA12 (0.58) CA1CA2CA12CA4CA7
SCHEMBL19971754 0.79 HPGD (0.65) CA1CA2CA12CA9TP53
SCHEMBL1928662 0.79 CA12 (0.85) CA1CA2CA12CA4CA7
SCHEMBL23486696 0.79 CA12 (0.56) CA1CA2CA12CA4CA7
SCHEMBL6243996 0.79 CA12 (0.85) CA1CA2CA12CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274184-B1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2021-05-05 EP claimed
US-10265985-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-04-23 US claimed
US-20180079243-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-03-22 US claimed
US-10265985-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-04-23 US disclosed
US-20180079243-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-03-22 US disclosed