SCHEMBL19971753

SCHEMBL19971753

O=C(Nc1ccccc1)NS(=O)(=O)Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.67
TP53 P04637 1/20 0.59
EPHX1 P07099 1/20 0.59
TSHR P16473 1/20 0.59
EPHX2 P34913 1/20 0.59
CDK9 P50750 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CLK4 Q9HAZ1 1/20 0.59
LMNA P02545 1/20 0.54
CYP2C9 P11712 1/20 0.54
CASP3 P42574 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA9 Q16790 3/20 0.51
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
TAAR1 Q96RJ0 2/20 0.48
NPC1 O15118 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8318477 0.82 ACP1 (0.74) ACP1TP53EPHX1TSHREPHX2
SCHEMBL7086468 0.82 KEAP1 (0.50) ACP1TP53EPHX1TSHREPHX2
SCHEMBL28382803 0.81 ACP1 (0.62) ACP1TP53EPHX1TSHREPHX2
SCHEMBL19971761 0.81 CA1 (0.56) TP53LMNACA12CA1CA2
SCHEMBL3802959 0.78 CA1 (0.52) ACP1TP53EPHX1TSHREPHX2
SCHEMBL3053462 0.78 HDAC2 (0.54) LMNACA12CA1CA2CA9
SCHEMBL24713108 0.78 ACP1 (0.69) ACP1TP53EPHX1TSHREPHX2
SCHEMBL4421237 0.78 ACP1 (0.69) ACP1TP53EPHX1TSHREPHX2
SCHEMBL31395420 0.78 ACP1 (0.69) ACP1TP53EPHX1TSHREPHX2
SCHEMBL4202296 0.78 ACP1 (0.69) ACP1TP53EPHX1TSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274184-B1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2021-05-05 EP claimed
US-10265985-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-04-23 US claimed
US-20180079243-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-03-22 US claimed
US-12454144-B2 Heat-sensitive recording material comprising phenol-free organic colour developers MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2025-10-28 US disclosed
US-11752793-B2 Heat-sensitive recording material MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2023-09-12 US disclosed
EP-4200139-A1 HEAT-SENSITIVE RECORDING MATERIAL, AND HEAT-SENSITIVE RECORDING LAYER AND COATING COMPOSITION FOR PRODUCING SAME, CORRESPONDING USES AND METHOD Mitsubishi HiTec Paper Europe GmbH (DE) 2023-06-28 EP disclosed
US-20220363924-A1 Heat-Sensitive Recording Material Comprising Phenol-Free Organic Colour Developers MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2022-11-17 US disclosed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
WO-2022038242-A1 HEAT-SENSITIVE RECORDING MATERIAL, AND HEAT-SENSITIVE RECORDING LAYER AND COATING COMPOSITION FOR PRODUCING SAME, CORRESPONDING USES AND METHOD MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2022-02-24 WO disclosed
EP-3957488-A1 HEAT-SENSITIVE RECORDING MATERIAL AND HEAT-SENSITIVE RECORDING LAYER AND COATING COMPOSITION FOR ITS PRODUCTION, USES AND METHODS Mitsubishi HiTec Paper Europe GmbH (DE) 2022-02-23 EP disclosed
US-20200369062-A1 HEAT-SENSITIVE RECORDING MATERIAL MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2020-11-26 US disclosed
US-10265985-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-04-23 US disclosed
US-20180079243-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369062-A1 HEAT-SENSITIVE RECORDING MATERIAL SCN2A, SCN1A, CACNA1A ACP1 1766/4885TP53 2029/4885EPHX1 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.