Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972757 | 0.95 | CTSK (0.40) | CTSKCTSH | |
| SCHEMBL19982971 | 0.93 | PRSS1 (0.39) | — | |
| SCHEMBL19983033 | 0.93 | PRSS1 (0.39) | — | |
| SCHEMBL23023501 | 0.91 | CTSK (0.37) | CTSKCTSH | |
| SCHEMBL19982989 | 0.89 | CTSK (0.40) | CTSKCTSH | |
| SCHEMBL19982920 | 0.89 | CTSK (0.39) | CTSKCTSH | |
| SCHEMBL21113155 | 0.89 | CTSK (0.39) | CTSKCTSH | |
| SCHEMBL19982922 | 0.89 | CTSK (0.39) | CTSKCTSH | |
| SCHEMBL25661000 | 0.87 | CTSK (0.38) | CTSKCTSH | |
| SCHEMBL21152665 | 0.84 | ALB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512846-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |