Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | GLA | P06280 | 3/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.91 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142022 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL29440642 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| Bromide SCHEMBL31261167 | 0.94 | ALDH1A1 (0.97) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| Formaldehyde SCHEMBL28369375 | 0.92 | ALDH1A1 (0.94) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL10879416 | 0.87 | ALDH1A1 (0.83) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL28515379 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| Trifluoroacetic Acid SCHEMBL30450517 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL10004869 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL20348876 | 0.84 | ALDH1A1 (0.79) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 | |
| SCHEMBL29397438 | 0.83 | ALDH1A1 (0.77) | ALDH1A1KDM4EGLAL3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052877-A1 | REDOX ACTIVATABLE FLUORESCENT SENSORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-22 | — | — | WO | claimed |
| US-20210333263-A1 | REDOX ACTIVATABLE FLUORESCENT SENSORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-28 | — | — | US | disclosed |
| WO-2018052877-A1 | REDOX ACTIVATABLE FLUORESCENT SENSORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-22 | — | — | WO | disclosed |