Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008859 | 0.83 | IDO1 (0.33) | IDO1L3MBTL1MEN1NPC1GAA | |
| SCHEMBL1738833 | 0.80 | IDO1 (0.40) | IDO1L3MBTL1MEN1NPC1GAA | |
| SCHEMBL5088767 | 0.76 | SLC6A2 (0.50) | IDO1TAAR1ALDH1A1 | |
| SCHEMBL799906 | 0.73 | ESR1 (0.58) | IDO1TAAR1HTR2ACYP2A6PYCR1 | |
| SCHEMBL22527739 | 0.72 | TLR7 (0.36) | MEN1MAPTKMT2A | |
| SCHEMBL3412195 | 0.71 | MAOB (0.38) | IDO1L3MBTL1MEN1NPC1GAA | |
| SCHEMBL5185744 | 0.70 | KMT2A (0.41) | L3MBTL1MEN1NPC1MAPTRAB9A | |
| SCHEMBL12433178 | 0.70 | IDO1 (0.43) | IDO1L3MBTL1MEN1NPC1GAA | |
| SCHEMBL1737226 | 0.70 | ESR1 (0.43) | IDO1TAAR1HTR2ACYP2A6PYCR1 | |
| SCHEMBL8851233 | 0.70 | TAAR1 (0.40) | IDO1MEN1KMT2ATAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216726-A1 | Particles, Compositions and Methods for Ophthalmic and/or Other Applications | OXFORD FINANCE LLC | 2019-07-18 | — | — | US | disclosed |
| WO-2018053321-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216726-A1 | Particles, Compositions and Methods for Ophthalmic and/or Other Applications | MUC1, RAB5IF, PDE6C | IDO1 4171/4885L3MBTL1 4874/4885MEN1 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.