SCHEMBL19973072

SCHEMBL19973072

N#CC(C#N)=C1CCOCC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20990708 0.83 ALDH1A1 (0.44) ALDH1A1HSD17B10DRD2DRD3MEN1
SCHEMBL2786474 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10DRD2DRD3
Hydrochloric Acid SCHEMBL11032285 0.75 ALDH1A1 (0.43) ALDH1A1HSD17B10DRD2DRD3
SCHEMBL5508352 0.75 ALDH1A1 (0.60) ALDH1A1HSD17B10DRD2DRD3LMNA
SCHEMBL29031886 0.72
SCHEMBL3708976 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3LMNA
SCHEMBL19973070 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3LMNA
SCHEMBL13349939 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3LMNA
SCHEMBL19973082 0.70 ALDH1A1 (0.33) ALDH1A1HSD17B10DRD2DRD3MEN1
SCHEMBL17807528 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376041-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2024-11-14 US disclosed
US-12098115-B2 Methods and compositions for terpenoid synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-09-24 US disclosed
US-11952327-B2 Methods and compositions for terpenoid synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-04-09 US disclosed
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2024-01-25 US disclosed
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIV FLORIDA (US) 2019-09-05 US disclosed
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIV FLORIDA (US) 2019-09-05 US disclosed
WO-2018053322-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952327-B2 Methods and compositions for terpenoid synthesis SQLE, GGPS1, LSS ALDH1A1 1162/4885HSD17B10 686/4885DRD2 1203/4885
US-20240376041-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS ALDH1A1 1162/4885HSD17B10 686/4885DRD2 1203/4885
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS ALDH1A1 1162/4885HSD17B10 686/4885DRD2 1203/4885
US-12098115-B2 Methods and compositions for terpenoid synthesis SQLE, GGPS1, LSS ALDH1A1 1162/4885HSD17B10 686/4885DRD2 1203/4885
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS ALDH1A1 1353/4885HSD17B10 675/4885DRD2 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.