Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18600867 | 0.78 | AR (0.44) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL1647131 | 0.78 | AR (0.44) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4638799 | 0.76 | KMT2A (0.60) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL31172240 | 0.76 | KMT2A (0.60) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL15475131 | 0.76 | HPGD (0.43) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2362378 | 0.76 | MAOA (0.58) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL18304358 | 0.75 | MAOB (0.62) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL29034464 | 0.74 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1CHRNB2 | |
| SCHEMBL810521 | 0.74 | MAOB (0.63) | MAPTALDH1A1KMT2AMEN1CHRNB2 | |
| SCHEMBL19065126 | 0.74 | KMT2A (0.52) | MAPTALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052903-A1 | RORγ MODULATORS | THE SCRIPPS RESEARCH INTITUTE (US) | 2018-03-22 | — | — | WO | disclosed |