Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106298 | 1.00 | CES2 (0.48) | CES2CES1ALDH1A1TP53MEN1 | |
| SCHEMBL3409269 | 0.93 | CES2 (0.56) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL18597115 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL20838327 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL21318254 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL16431121 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL21448711 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL28292434 | 0.91 | CES2 (0.59) | CES2CES1ALDH1A1MEN1FAAH | |
| SCHEMBL105901 | 0.84 | — | — | |
| SCHEMBL14929028 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512351-A1 | COMPOSITIONS AND METHODS FOR IMPROVING TASTE OF NON-NUTRITIVE SWEETENERS | Pepsico, Inc. (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053135-A9 | COMPOSITIONS AND METHODS FOR IMPROVING TASTE OF NON-NUTRITIVE SWEETENERS | PEPSICO, INC. (US) | 2019-04-18 | — | — | WO | disclosed |
| WO-2018053135-A1 | COMPOSITIONS AND METHODS FOR IMPROVING TASTE OF NON-NUTRITIVE SWEETENERS | PEPSICO, INC. (US) | 2018-03-22 | — | — | WO | disclosed |