Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136193 | 0.82 | POLB (0.52) | POLBALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL20636715 | 0.81 | POLB (0.48) | POLBALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL16593897 | 0.81 | POLB (0.48) | POLBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL18506073 | 0.78 | POLB (0.46) | POLBALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL22901345 | 0.78 | POLB (0.52) | POLBALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL20189025 | 0.77 | POLB (0.46) | POLBALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL31141582 | 0.77 | POLB (0.48) | POLBALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL23507228 | 0.76 | POLB (0.50) | POLBALDH1A1SMN1; SMN2AGBL2DRD2 | |
| SCHEMBL19711951 | 0.76 | POLB (0.47) | POLBALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL19711948 | 0.76 | POLB (0.47) | POLBALDH1A1KDM4EMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512847-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED BICYCLES | BAYER CROPSCIENCE AG (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-20190375766-A1 | PROCESS FOR PREPARING HALOGENATED BICYCLIC SYSTEMS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-12-12 | — | — | US | disclosed |
| EP-3512847-A1 | METHOD FOR PRODUCING HALOGENATED BICYCLIC COMPOUNDS | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050515-A1 | METHOD FOR PRODUCING HALOGENATED BICYCLIC COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190375766-A1 | PROCESS FOR PREPARING HALOGENATED BICYCLIC SYSTEMS | INTS6, POLR2H, NQO2 | POLB 74/4885ALDH1A1 2681/4885KDM4E 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.