Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136193 | 0.82 | POLB (0.52) | POLBALDH1A1KDM4ESMN1; SMN2MAOB | |
| SCHEMBL16593897 | 0.81 | POLB (0.48) | POLBALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL19974042 | 0.81 | POLB (0.48) | POLBALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL20189025 | 0.80 | POLB (0.46) | POLBALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL22901345 | 0.78 | POLB (0.52) | POLBALDH1A1KDM4EMETRAB9A | |
| SCHEMBL18506073 | 0.78 | POLB (0.46) | POLBALDH1A1KDM4ESMN1; SMN2MAOB | |
| SCHEMBL31141582 | 0.77 | POLB (0.48) | POLBALDH1A1KDM4ESMN1; SMN2MET | |
| SCHEMBL23507228 | 0.76 | POLB (0.50) | POLBALDH1A1SMN1; SMN2METDRD2 | |
| SCHEMBL19711948 | 0.76 | POLB (0.47) | POLBALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL19711951 | 0.76 | POLB (0.47) | POLBALDH1A1KDM4ESMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| CN-108884091-B | Condensed heterocyclic compound and pest control agent | 日产化学株式会社 | 2021-04-13 | — | — | CN | disclosed |
| EP-3766881-A1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-10765116-B2 | 2-[3-(alkylsulfonyl)-2H-indazol-2-yl]-3H-imidazo[4,5-B]pyridine derivatives and similar compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-09-08 | — | — | US | disclosed |
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-07-16 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-01-28 | — | — | US | disclosed |
| US-20190274306-A1 | 2-[3-(ALKYLSULFONYL)-2H-INDAZOL-2-YL]-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-12 | — | — | US | disclosed |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | US | disclosed |
| EP-3428166-A1 | CONDENSED HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Corporation (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885ALDH1A1 268/4885KDM4E 2736/4885 |
| US-20190274306-A1 | 2-[3-(ALKYLSULFONYL)-2H-INDAZOL-2-YL]-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | API5, ACHE, ATXN2 | POLB 4844/4885ALDH1A1 989/4885KDM4E 1034/4885 |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, BCHE | POLB 4096/4885ALDH1A1 264/4885KDM4E 2452/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885ALDH1A1 268/4885KDM4E 2736/4885 |
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4343/4885ALDH1A1 1097/4885KDM4E 3067/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | POLB 4837/4885ALDH1A1 268/4885KDM4E 2736/4885 |
| US-10765116-B2 | 2-[3-(alkylsulfonyl)-2H-indazol-2-yl]-3H-imidazo[4,5-B]pyridine derivatives and similar compounds as pesticides | API5, ACHE, ATXN2 | POLB 4844/4885ALDH1A1 989/4885KDM4E 1034/4885 |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | CHRM1, HCRTR1, NR4A1 | POLB 4742/4885ALDH1A1 707/4885KDM4E 3647/4885 |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4393/4885ALDH1A1 1147/4885KDM4E 3163/4885 |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, ACHE, BCHE | POLB 4096/4885ALDH1A1 264/4885KDM4E 2452/4885 |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NR4A1, CHRM1, NR1D2 | POLB 4393/4885ALDH1A1 1147/4885KDM4E 3163/4885 |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4297/4885ALDH1A1 1121/4885KDM4E 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.