Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503399 | 0.85 | MGLL (0.50) | MGLLABHD6CYP2D6PTGDR2FAAH | |
| SCHEMBL20167156 | 0.84 | MGLL (0.49) | MGLLABHD6CYP2D6PTGDR2FAAH | |
| SCHEMBL18064897 | 0.83 | MGLL (0.53) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL25274875 | 0.82 | KDM4E (0.55) | MGLLFAAHKDM4EALDH1A1LMNA | |
| SCHEMBL20168556 | 0.82 | MGLL (0.47) | MGLLABHD6CYP2D6PTGDR2FAAH | |
| SCHEMBL29531253 | 0.81 | MGLL (0.71) | MGLLABHD6CYP2D6FAAHPLA2G7 | |
| SCHEMBL20570097 | 0.81 | MGLL (0.48) | MGLLABHD6CYP2D6PTGDR2FAAH | |
| SCHEMBL15093961 | 0.81 | MGLL (0.71) | MGLLABHD6CYP2D6FAAHPLA2G7 | |
| SCHEMBL20503460 | 0.81 | MGLL (0.45) | MGLLABHD6CYP2D6PTGDR2FAAH | |
| Hydrochloric Acid SCHEMBL20167340 | 0.80 | MGLL (0.70) | MGLLABHD6CYP2D6FAAHPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3541822-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| EP-3515897-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018217805-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |
| WO-2018093946-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |