Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974281 | 0.71 | HDAC4 (0.40) | AKR1C1HDAC4CYP19A1CYP11B2AR | |
| SCHEMBL19974324 | 0.67 | AKR1C1 (0.49) | AKR1C1HDAC4 | |
| SCHEMBL9480750 | 0.65 | SLC6A4 (0.49) | AKR1C1HDAC4 | |
| SCHEMBL10950625 | 0.65 | GLRA3 (0.39) | AKR1C1 | |
| SCHEMBL2153499 | 0.64 | ALDH1A1 (0.38) | AR | |
| SCHEMBL11902425 | 0.64 | AKR1C1 (0.47) | AKR1C1HDAC4 | |
| SCHEMBL28334267 | 0.64 | AKR1C1 (0.47) | AKR1C1HDAC4 | |
| SCHEMBL3188765 | 0.63 | HDAC4 (0.48) | AKR1C1HDAC4 | |
| SCHEMBL10703712 | 0.63 | AKR1C1 (0.47) | AKR1C1 | |
| SCHEMBL8849891 | 0.63 | AKR1C1 (0.47) | AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515897-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |