Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | USP4 | Q13107 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359891 | 0.79 | KMT2A (0.52) | MEN1KMT2ACPA1ALDH1A1MAPK1 | |
| SCHEMBL29020257 | 0.76 | SMN1; SMN2 (0.50) | CYP19A1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7279175 | 0.75 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL3961101 | 0.74 | — | — | |
| SCHEMBL19974645 | 0.72 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL19974760 | 0.71 | HRH3 (0.40) | MEN1KMT2AALDH1A1HRH3TSHR | |
| SCHEMBL538524 | 0.70 | CYP19A1 (0.76) | CYP19A1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10573912 | 0.70 | MAPK1 (0.61) | CYP19A1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL2216126 | 0.70 | CYP19A1 (0.69) | CYP19A1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL29020312 | 0.70 | SMN1; SMN2 (0.55) | CYP19A1KMT2ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512840-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | Tseng, Yufeng, Jane (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053161-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL TAIWAN UNIVERSITY (TW) | 2018-03-22 | — | — | WO | disclosed |