SCHEMBL19974910

SCHEMBL19974910

CC(NC(=O)Cc1ccccc1)C(=O)C(=O)NCC1CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
CNR2 P34972 6/20 0.46
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 2/20 0.44
PSMB8 P28062 1/20 0.44
PSMB5 P28074 1/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.43
CNR1 P21554 1/20 0.43
EPHX2 P34913 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
CTSD P07339 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21176278 0.82 PREP (0.47) ALDH1A1RAB9AKDM4EHPGD
SCHEMBL2409477 0.79 NPC1 (0.60) MEN1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL19974977 0.79 PSMB8 (0.46) POLBCNR2MEN1CYP1A2KMT2A
SCHEMBL19974906 0.78 F2 (0.43) MEN1KMT2AALDH1A1SIGMAR1
SCHEMBL19975138 0.77 SMN1; SMN2 (0.50) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL19975210 0.77 SMN1; SMN2 (0.53) MEN1KMT2AALDH1A1KDM4E
SCHEMBL19975149 0.76 SMN1; SMN2 (0.55) MEN1KMT2AALDH1A1
SCHEMBL19975398 0.76 MAPK14 (0.43) MEN1CYP1A2KMT2ANPC1RAB9A
SCHEMBL19974990 0.76 MAPK14 (0.43) MEN1CYP1A2KMT2ANPC1RAB9A
SCHEMBL19974989 0.76 MAPK14 (0.43) MEN1CYP1A2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C POLB 833/4885CNR2 2339/4885MEN1 4331/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C POLB 617/4885CNR2 2681/4885MEN1 4361/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C POLB 833/4885CNR2 2339/4885MEN1 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.