PLA2G4C — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL30007459	0.92	2/20
SCHEMBL2729840	0.74	2/20
SCHEMBL2729842	0.74	2/20
SCHEMBL3686137	0.74	2/20
SCHEMBL22187659	0.74	2/20
SCHEMBL22222834	0.74	2/20
SCHEMBL22222879	0.74	2/20
SCHEMBL22222880	0.74	2/20
SCHEMBL29367824	0.74	2/20
SCHEMBL22222825	0.65	2/20
SCHEMBL3690078	0.56	2/20
SCHEMBL22222878	0.56	2/20
SCHEMBL1684101	0.54	2/20
SCHEMBL1684102	0.54	2/20
SCHEMBL16908822	0.54	2/20
SCHEMBL19689390	0.54	2/20
SCHEMBL22187692	0.54	2/20
SCHEMBL22222829	0.54	2/20
SCHEMBL22222832	0.54	2/20
SCHEMBL29380622	0.54	2/20

Clinical trials — most relevant to PLA2G4C by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study	PHASE4	COMPLETED
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)	PHASE4	COMPLETED
A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis	PHASE3	COMPLETED
European Celecoxib Trial in Primary Breast Cancer	PHASE3	COMPLETED
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes	PHASE3	UNKNOWN
Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM	PHASE3	COMPLETED
Montelukast in Parkinson Disease	PHASE2/PHASE3	RECRUITING
Montelukast for Early Life Wheezing	PHASE2/PHASE3	COMPLETED
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
Ibuprofen Versus Acetaminophen for Treatment of Mild Traumatic Brain Injury	PHASE2	WITHDRAWN
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke	nan	COMPLETED
Role of Anti-mouse PLA2R1 ELISA in Membranous Nephropathy	nan	COMPLETED
Mucomyst for Hepatitis C	nan	SUSPENDED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Role of PLA2G1B During HIV Infection	nan	UNKNOWN
Positron Emission Tomography (PET) to Study Brain Signaling	nan	COMPLETED
PET Imaging of DHA Metabolism	nan	COMPLETED
Molecular Markers of Human Sperm Function	nan	WITHDRAWN
LDL-Apheresis for FSGS CardioRenal Outcomes	nan	COMPLETED
Investigation of Lipoxin A4, Annexin A1 and Interleukin-1 Beta Levels in Individuals With Periodontitis.	nan	COMPLETED
An Outcome Analysis of Primary Membranous Nephropathy	nan	RECRUITING
Lipoprotein-associated Phospholipase A2 in Patients With Type 2 Diabetes	nan	COMPLETED
Relation Between Prostaglandin E2 Metabolite Levels and the Development of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Neonates	nan	RECRUITING
Correlation and Clinical Utility of Urinary Biomarker in Membranous Glomerulonephritis	nan	UNKNOWN
Autotaxin (ATX) as a Marker for Breast Cancer	nan	UNKNOWN
Obinutuzumab in the Management of Idiopathic Membranous Nephropathy	nan	UNKNOWN
High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions	nan	COMPLETED
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia	nan	UNKNOWN
Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PLA2G4C binder may also engage these)

Protein	Name	Similarity
P0C871	—	0.986	P0C871 →
Q50L41	—	0.984	Q50L41 →
Q68DD2	—	0.984	Q68DD2 →
Q64GA5	—	0.984	Q64GA5 →
Q3MJ16	—	0.982	Q3MJ16 →
Q50L42	—	0.977	Q50L42 →
Q50L43	—	0.976	Q50L43 →
P50392	—	0.975	P50392 →
PLA2G4B	Cytosolic phospholipase A2 beta	0.975	landscape →
Q86XP0	—	0.974	Q86XP0 →
B1WAZ6	—	0.970	B1WAZ6 →
Q7T0T9	—	0.970	Q7T0T9 →
Q9TT38	—	0.970	Q9TT38 →
Q5R8A5	—	0.970	Q5R8A5 →
A4IFJ5	—	0.969	A4IFJ5 →
P47713	—	0.969	P47713 →
Q7TPV4	—	0.969	Q7TPV4 →
P50393	—	0.968	P50393 →
Q9D2K4	—	0.968	Q9D2K4 →
O14830	—	0.967	O14830 →
Q2KI18	—	0.967	Q2KI18 →
O77793	—	0.967	O77793 →
P0C548	—	0.967	P0C548 →
PLA2G4A	Cytosolic phospholipase A2	0.967	landscape →
O35385	—	0.967	O35385 →
Q8R2H5	—	0.967	Q8R2H5 →
Q149M9	—	0.966	Q149M9 →
O95479	—	0.966	O95479 →
Q1LZ50	—	0.965	Q1LZ50 →
Q9JHI2	—	0.965	Q9JHI2 →