Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498838 | 0.88 | HPGD (0.72) | HPGDTP53GLAAPEX1ALDH1A1 | |
| SCHEMBL29809770 | 0.88 | HPGD (0.72) | HPGDTP53GLAAPEX1ALDH1A1 | |
| SCHEMBL19974733 | 0.84 | CTSD (0.48) | APEX1ALDH1A1MAPTLMNAPDE10A | |
| SCHEMBL28404148 | 0.77 | HPGD (0.74) | HPGDTP53GLAALDH1A1LMNA | |
| SCHEMBL29936750 | 0.77 | HPGD (0.74) | HPGDTP53GLAALDH1A1LMNA | |
| SCHEMBL19974682 | 0.76 | CTSD (0.51) | APEX1ALDH1A1MAPTLMNAPDE10A | |
| SCHEMBL19975254 | 0.76 | CTSD (0.47) | APEX1ALDH1A1MAPTLMNAPDE10A | |
| SCHEMBL19974969 | 0.75 | MAPT (0.51) | APEX1ALDH1A1MAPTLMNAPDE10A | |
| SCHEMBL13040229 | 0.74 | HPGD (0.74) | HPGDTP53GLAAPEX1ALDH1A1 | |
| SCHEMBL18641776 | 0.74 | HPGD (0.74) | HPGDTP53GLAAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512836-A1 | ANTIVIRAL COMPOUNDS | Haplogen GmbH (AT) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |