Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 11/20 | 0.38 |
| ▸ | JAK1 | P23458 | 10/20 | 0.38 |
| ▸ | TYK2 | P29597 | 9/20 | 0.38 |
| ▸ | STAT3 | P40763 | 9/20 | 0.38 |
| ▸ | JAK3 | P52333 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854337 | 0.80 | — | — | |
| SCHEMBL14964510 | 0.77 | JAK2 (0.46) | ALDH1A1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL23022153 | 0.77 | JAK2 (0.38) | ALDH1A1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL28826010 | 0.77 | MAPT (0.41) | ALDH1A1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL1662812 | 0.77 | MAPT (0.41) | ALDH1A1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL28235207 | 0.75 | — | — | |
| SCHEMBL5871164 | 0.75 | — | — | |
| SCHEMBL19116686 | 0.74 | KMT2A (0.41) | KMT2AJAK2JAK1TYK2STAT3 | |
| SCHEMBL30182641 | 0.74 | JAK2 (0.39) | ALDH1A1KMT2AJAK2JAK1TYK2 | |
| SCHEMBL14962175 | 0.74 | KDM5A (0.44) | MAPK1JAK2JAK1TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051309-A1 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2025-02-13 | — | — | US | disclosed |
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |
| US-9926319-B2 | Pyridyl piperidines | MERCK PATENT GMBH (DE) | 2018-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051309-A1 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DUSP2, MKNK2, DUSP22 | ALDH1A1 4336/4885KMT2A 506/4885TSHR 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.