Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 11/20 | 0.79 |
| ▸ | LGALS7; LGALS7B | P47929 | 4/20 | 0.70 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.70 |
| ▸ | LGALS9 | O00182 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.51 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681085 | 1.00 | LGALS3 (0.79) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL19976179 | 0.94 | LGALS3 (0.79) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL17681096 | 0.94 | LGALS3 (0.79) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL5356735 | 0.92 | LGALS3 (0.82) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL5356738 | 0.92 | LGALS3 (0.82) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL19976176 | 0.92 | LGALS3 (0.75) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL17681095 | 0.92 | LGALS3 (0.75) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL17681079 | 0.88 | LGALS3 (1.00) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL19976177 | 0.88 | LGALS3 (1.00) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 | |
| SCHEMBL5354309 | 0.85 | LGALS3 (0.84) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9921230-B2 | Methods for diagnosis and treatment of concussion or brain injury | RHODE ISLAND HOSPITAL (US) | 2018-03-20 | — | — | US | disclosed |