SCHEMBL19976368

SCHEMBL19976368

Cc1c(N[C@@H](C)[C@H](C)O)ccc(C#N)c1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.51
PGR P06401 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1365327 0.83 AR (0.46) ARPGR
SCHEMBL1291443 0.83 AR (0.46) ARPGR
SCHEMBL1291489 0.81 AR (0.44) ARPGR
SCHEMBL19970450 0.81 AR (0.44) ARPGR
SCHEMBL1291488 0.81 AR (0.44) ARPGR
SCHEMBL12140330 0.80 AR (0.40) ARPGR
SCHEMBL19976339 0.78 AR (0.56) ARPGR
SCHEMBL12138411 0.78 AR (0.56) ARPGR
SCHEMBL1291586 0.76 AR (0.45) ARPGR
SCHEMBL1291583 0.76 AR (0.45) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920044-B2 Selective androgen receptor modulators RADIUS PHARMACEUTICALS, INC. (US) 2018-03-20 US disclosed