Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18964683 | 1.00 | SUCNR1 (0.36) | SUCNR1KDM4EGMNNLMNAPMP22 | |
| SCHEMBL19303282 | 0.86 | — | — | |
| SCHEMBL18541710 | 0.86 | — | — | |
| SCHEMBL9380448 | 0.80 | — | — | |
| SCHEMBL5065181 | 0.76 | SUCNR1 (0.39) | SUCNR1KDM4ELMNA | |
| SCHEMBL18530044 | 0.76 | SUCNR1 (0.39) | SUCNR1KDM4ELMNA | |
| SCHEMBL20888679 | 0.76 | SUCNR1 (0.39) | SUCNR1KDM4ELMNA | |
| SCHEMBL5035096 | 0.76 | SUCNR1 (0.39) | SUCNR1KDM4ELMNA | |
| SCHEMBL18530019 | 0.76 | SUCNR1 (0.39) | SUCNR1KDM4ELMNA | |
| SCHEMBL15859806 | 0.75 | PPM1B (0.34) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919057-B2 | Compounds comprising self-immolative group | LEGOCHEM BIOSCIENCES, INC. (KR) | 2018-03-20 | — | — | US | disclosed |