SCHEMBL5065181

SCHEMBL5065181

O=C(O)C1OCC(O)C1O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.39
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
IDUA P35475 1/20 0.31
CA1 P00915 3/20 0.30
CA9 Q16790 2/20 0.30
CA2 P00918 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20888679 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL5035096 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL18530044 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL18530019 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL24212766 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL1669031 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL21097517 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL13618641 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL23720424 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL12346259 0.95 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017030684-A1 DEHYDRATIVE CYCLIZATION OF PENTITOLS USING WATER-TOLERANT LEWIS ACID CATALYSTS UNDER MILD CONDITIONS AND DERIVATIVES ARCHER DANIELS MIDLAND COMPANY (US) 2017-02-23 WO disclosed
WO-2008015120-A1 λ5-Si - SILICATE-FUNCTIONAL PREPOLYMERS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed