Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976412 | 0.96 | LMNA (0.52) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17502007 | 0.88 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17502010 | 0.88 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17501989 | 0.87 | LMNA (0.60) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17501955 | 0.86 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17501962 | 0.86 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17501958 | 0.86 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17501966 | 0.86 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL29709612 | 0.86 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1TSHR | |
| SCHEMBL17502081 | 0.85 | LMNA (0.59) | LMNACYP2D6ALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |