Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602351 | 0.91 | HPGD (0.50) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL101437 | 0.90 | HPGD (0.56) | HPGDTSHRCYP2D6CYP2C19MMP1 | |
| SCHEMBL14577252 | 0.89 | HPGD (0.53) | HPGDTSHRCYP2D6CYP2C19MMP1 | |
| SCHEMBL23729797 | 0.86 | HPGD (0.44) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL25524815 | 0.86 | LMNA (0.43) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL30503498 | 0.84 | HPGD (0.43) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL23729880 | 0.84 | HPGD (0.43) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL18383666 | 0.84 | HPGD (0.45) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL101552 | 0.84 | HPGD (0.45) | HPGDCYP2D6CYP2C19MMP1MMP8 | |
| SCHEMBL12751964 | 0.83 | TSHR (0.40) | HPGDTSHREPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |