Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508350 | 0.93 | GAA (0.46) | HTTGAAL3MBTL1TSHRKMT2A | |
| Ot-551 SCHEMBL3692374 | 0.93 | GAA (0.46) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL1535623 | 0.93 | GAA (0.46) | HTTGAAL3MBTL1TSHRKMT2A | |
| Ot-551 SCHEMBL3696276 | 0.92 | GAA (0.48) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL21163395 | 0.90 | GAA (0.42) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL19937416 | 0.88 | GAA (0.35) | HTTGAA | |
| SCHEMBL19636872 | 0.87 | GAA (0.42) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL19884611 | 0.86 | GAA (0.41) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL19636873 | 0.85 | GAA (0.43) | HTTGAAL3MBTL1TSHRKMT2A | |
| SCHEMBL13554257 | 0.84 | GAA (0.40) | HTTGAAL3MBTL1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920248-B2 | Compounds and liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-03-20 | — | — | US | disclosed |