Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300413 | 0.78 | KDM4E (0.40) | — | |
| SCHEMBL9228352 | 0.77 | KDM4E (0.39) | — | |
| SCHEMBL24995661 | 0.77 | KDM4E (0.39) | — | |
| SCHEMBL27878179 | 0.73 | KIF11 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL28342609 | 0.73 | KIF11 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL30302596 | 0.72 | KIF11 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL10579678 | 0.71 | KDM4E (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL10580092 | 0.71 | KDM4E (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL10580574 | 0.71 | KDM4E (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL10580858 | 0.71 | KDM4E (0.46) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |