Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984377 | 0.86 | KMT2A (0.42) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL363481 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL2328687 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5287541 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25270261 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25267924 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25267373 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25240227 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL1137200 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL4068798 | 0.74 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078477-A1 | Method of Coloring Hair with Washfast Yellow Imidazolium Direct Dye Compounds | WELLA OPERATIONS US, LLC | 2018-03-22 | — | — | US | disclosed |
| US-9918919-B1 | Method of coloring hair with washfast yellow imidazolium direct dye compounds | NOXELL CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078477-A1 | Method of Coloring Hair with Washfast Yellow Imidazolium Direct Dye Compounds | WASHC4, TYR, WASHC5 | TLR8 3142/4885POLB 1492/4885ALDH1A1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.