SCHEMBL1997727

SCHEMBL1997727

OB(O)c1ccc(Nc2c(-c3ccccc3)ccc3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
MGLL Q99685 1/20 0.43
TRPV1 Q8NER1 3/20 0.40
ATM Q13315 2/20 0.38
KDM1A O60341 5/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
ENPP2 Q13822 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
CDC25B P30305 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4979017 0.85 HSD17B10 (0.48) ATMKDM1AALDH1A1HPGDTP53
SCHEMBL4232444 0.83 ALDH1A1 (0.42) ATMKDM1AALDH1A1HPGDTP53
SCHEMBL6405547 0.81 ABCG2 (0.48) ATMKDM1AALDH1A1HPGDTP53
SCHEMBL15400423 0.79 ALDH1A1 (0.44) ATMALDH1A1HPGDTP53CYP3A4
SCHEMBL4239262 0.78 KDM1A (0.53) ATMKDM1AALDH1A1HPGDTP53
SCHEMBL4236618 0.78 ABCG2 (0.46) ATMKDM1AALDH1A1HPGDTP53
SCHEMBL23780947 0.76 ALDH1A1 (0.41) CA1CA2ATMALDH1A1HPGD
SCHEMBL31367625 0.76 CA1 (0.53) CA1CA2MGLLTRPV1CA4
SCHEMBL4241058 0.76 KDM1A (0.41) ATMKDM1AALDH1A1HPGDKDM4E
SCHEMBL2869307 0.75 KDM1A (0.46) ATMKDM1AALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2335298-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES Merck Patent GmbH (DE) 2011-06-22 EP disclosed
WO-2010040438-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2010-04-15 WO disclosed