Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997784 | 0.90 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL3504273 | 0.75 | NR1H2 (0.41) | NR1H2NR1H3 | |
| SCHEMBL5308618 | 0.72 | NR1H2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL2000480 | 0.71 | TSHR (0.45) | — | |
| SCHEMBL2000298 | 0.70 | KMT2A (0.43) | — | |
| SCHEMBL2003034 | 0.70 | MEN1 (0.41) | — | |
| SCHEMBL2001082 | 0.69 | ESR1 (0.40) | NR1H2 | |
| SCHEMBL1999834 | 0.68 | NR1H2 (0.33) | NR1H2NR1H3 | |
| SCHEMBL2006277 | 0.67 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL1997782 | 0.64 | NR1H2 (0.45) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960380-B2 | Non-anilinic derivatives of isothiazol-3(2H)-one 1,1-dioxides as liver X receptor modulators | ASTRAZENECA AB (SE) | 2011-06-14 | — | — | US | disclosed |